*Based on % of patients reporting problems using the EQ-5D-5L. The EQ-5D-5L is a self-assessed, health related, quality of life questionnaire. The scale measures quality of life on a 5-component scale including mobility, self-care, usual activities, pain/discomfort, and anxiety/depression.

**Based on Atrial Fibrillation Effect on Quality of Life (AFEQT) survey score.